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Professors David Baker and Neil King use advanced protein modeling software and nanoparticle technology to develop better vaccines. Their approach has already led to an approved COVID-19 vaccine and more effective flu vaccine that has completed Phase I trials. David Baker won the Nobel Prize in Chemistry in 2024.

Four professionals share how our career advising grantees — Probably Good, High Impact Medicine, and High Impact Professionals — helped them find paths to greater impact.

Saad Bhamla is a key figure in the frugal innovation movement, which seeks to build cheaper versions of existing scientific tools. His latest innovation, a portable device to test tuberculosis and other diseases, could well be another consequential contribution to global public health.

In dozens of low- and middle-income countries, much of the paint supply contains dangerous amounts of lead. The Lead Exposure Elimination Project is working to end this public health crisis, which has received little attention from the global health community relative to its devastating effects.

The Open Wing Alliance (OWA), a coalition of advocacy groups, has persuaded more than 3,000 food companies worldwide to shift to using cage-free eggs, through a mix of negotiation and public campaigns. Thanks to OWA and other advocates, over 250 million hens have been spared from confinement.